Clemson vs. Duke Picks, Expert NCAAF Best Bets & Odds: Mon, 9/4 on ESPN

Duke posted its first winning season in four years in 2022, going 9-4 and defeating Central Florida, 30-13, in the Military Bowl. Head coach Mike Elko was named ACC Coach of the Year in his first season. His Blue Devils face a difficult task starting off Year 2 as they host No. 9 Clemson in Durham for the first time in 11 years on Monday.

The Tigers lost three games for the second straight season, uncharacteristic for them the past several years under coach Dabo Swinney. Cade Klubnik is the starting quarterback from the get-go and he goes head-to-head with Blue Devils gunslinger Riley Leonard. This Labor Day matchup should be exciting.

What will happen in this ACC matchup? Let’s dive into our Clemson vs. Duke picks, available at FanDuel Sportsbook.

CLEMSON VS. DUKE PREDICTION: UNDER 55.5 [-110 ODDS at FandDuel Sportsbook]

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CFB Week 1 Prediction for Clemson Tigers vs. Duke Blue Devils

What a great season opener for Duke to show how much it's grown under Elko. Clemson is coming in with something to prove after sliding in the second half of last season. Will Shipley, who made first-team All-ACC in two positions last year, returns after rushing for 1,182 yards and 15 touchdowns last fall. He will help ease Klubnik’s transition into the full-time starting role. Duke quarterback Riley Leonard has a great 2022 season, throwing for 2,967 yards and 20 touchdowns and running for another 699 yards and 13 scores. He has Jaylon Coleman (480 yards rushing, 4 TDs) behind him and Jalon Calhoun (62 catches, 873 yards, 4 TDs) to throw to.

There is a good deal of offensive firepower on both teams, but the defenses aren’t going anywhere either. The over/under for this game is 55.5 points with FanDuel Sportsbook. Clemson only surpassed that total in three games last year. Our bet here is that the two teams will play close to that number, but still go under.

NCAAF Best Bets & Clemson vs. Duke Picks for Week 1 Featuring Riley Leonard to throw over 1.5 TD passes

There are several Clemson vs. Duke picks that we like for this season opener. One of them involves Duke standout quarterback Riley Leonard. Clemson QB Cade Klubnik will get more publicity coming in being the former 5-star recruit that took over during the ACC championship game last year, but Leonard is the returning All-ACC pick. He threw 20 touchdown passes last year and he is a good bet to surpass those numbers this fall. Plus, this game will most likely require him to throw a good deal to keep pace with the Tigers.

FanDuel Sportsbook currently lists odds of (+194) for Leonard to throw over 1.5 touchdown passes. That means if you bet $100 on this player prop, and Leonard throws two or more TD passes, you win $194. This is our favorite of all the Clemson vs. Duke picks available, in terms of odds.

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How to Collect Bonuses Totalling $300 at FanDuel Sportsbook for Betting $5 on Riley Leonard to Throw Over 1.5 TD Passes

You can bet on Duke quarterback Riley Leonard to throw over 1.5 touchdown passes at FanDuel Sportsbook, which has a great promotion for you to take advantage of right now. When new customers sign up for a FanDuel Sportsbook account using this link, they can wager $5 on their first bet and get $200 in bonus bets instantly. That’s regardless of if that first wager, like this one on Leonard’s touchdown passes versus Clemson, wins or loses. And that’s not all. You’ll also get $100 off the NFL Sunday Ticket package as well. That’s $300 in bonuses for making as little as a $5 bet.

Just claim this special FanDuel sign-up bonus and register for a new account, find the Clemson vs. Duke picks you are interested in, and choose one to make your initial wager on and unlock those $300 in bonuses right now.

Latest Betting Odds, Lines & Spread for Clemson vs. Duke on Monday, 9/4 via FanDuel

Our experts backed their Clemson vs. Duke picks at FanDuel, but you can also fade or follow this selection at DraftKings Sportsbook. All new DraftKings members can risk $5 on any of these picks and no matter what happens, they will receive $200 in bonus bets.

The spread for this Clemson vs. Duke matchup has the Blue Devils Tigers as 13-point underdogs at (-110) odds with DraftKings Sportsbook. That means the bet would be a winner if Duke says within 12 points or even wins the game. If Duke can do that, a $110 wager would return $100 in profit.

Clemson is a 13-point favorite at DraftKings Sportsbook, meaning they must win by 14 points or more for the bet to be successful. The odds of that happening are -110 with DraftKings, meaning a $110 bet would deliver $100 in winnings if Clemson covers the spread.

However, as highlighted above, the game total for Clemson vs. Duke is set at 55.5 points, with -110 odds on both the over and the under. Whichever side you want to back, you’ll win $10 for every $11 staked if your bet is successful. To bet on any of these markets now, click here to join DraftKings Sportsbook, and you’ll receive $200 worth of free bets just for placing a $5 bet on our experts’ Clemson vs. Duke picks.

Duke Football Schedule for the 2023 Season

After this big season opener against Clemson, Duke has the chance to ring up some early season wins at home vs. Lafayette and Northwestern and at Connecticut before the schedule gets considerably more difficult. Elko faces his former employer when No. 13 Notre Dame comes to town at the end of September, followed by the full slate of ACC contests, highlighted by trips to pre-season Top 25 Florida State and North Carolina.

You can get a great jump start to the season by either following or fading our Clemson vs. Duke picks and joining FanDuel today to get $200 in bonus bets and $100 off the NFL Sunday Ticket package.

If you or a loved one has questions or needs to talk to a professional about gambling, call 1-800-GAMBLER or visit 1800gambler.net for more information.

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