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#8 USC vs. Colorado Picks, Predictions, Best Bets & Odds For Sat, 9/30

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The USC Trojans and the Colorado Buffaloes will play on Saturday to begin Week 5 of the college football season. The Fox Big Noon crew will once again be in Boulder to see Deion Sanders and this Colorado program play. The game will kick off at 12:00 PM ET and should be one of the most intriguing games of the entire day. We have provided you with our expert #8 USC vs. Colorado picks here.

USC travels to Boulder on Saturday for a PAC-12 matchup against this Colorado team, which has been the biggest story in all of college football. The Trojans are ranked #8 and have been one of the best teams in the entire country this season. Colorado experienced a wake-up call when they faced Oregon last week and will look to bounce back here to show they can compete against the best teams in the nation. We have highlighted our expert #8 USC vs. Colorado picks below with odds provided by BetMGM Sportsbook.

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#8 USC vs. Colorado Pick: USC -21.5 (-110 at BetMGM Sportsbook)

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#8 USC vs. Colorado Picks & Game Preview Ahead of Saturday, 9/30

The USC Trojans and the Colorado Buffaloes face off on Saturday inside Folsom Field for a PAC-12 matchup. This will be an interesting game between the second-highest-ranked PAC-12 team and the most popular team in the entire country. Colorado might be the most talked about team this season by the media, but we believe USC is the better overall team here. USC to cover the 21.5-point spread is our expert #8 USC vs. Colorado pick.

We expect USC to cover the spread here on the road because we saw last week how Colorado looked against a top-ranked team like Oregon. The Buffaloes looked completely different than they did to start the season as they got blown out from start to finish. Oregon looked like the better team by far, holding Colorado to just six points and shutting them out for the first three quarters of the game. That game gave us a good indication of what this Colorado team really is and we do not believe they can compete with USC. USC is on a similar talent level as Oregon, which is why their spread is our expert #8 USC vs. Oregon pick.

USC is one of the best teams in the entire country, so their spread is our expert #8 USC vs. Colorado pick. Follow this link to head to BetMGM Sportsbook to place a wager to take advantage of their current $1,500 first-bet promotion. Additionally, you can join Underdog Fantasy today for a $500 deposit match bonus.

#8 USC vs. Colorado Prediction and Best Bets

The USC Trojans’ spread offered at BetMGM is our expert prediction and best bet for the game on Saturday. As mentioned before, USC is the more talented team and should have great success on offense in this one. Their offense is led by Heisman Trophy winner Caleb Williams, who is projected to be the #1 overall pick in next year’s NFL draft. We do not think this Colorado defense will have an answer for this Caleb Williams-led offensive unit.

Colorado’s defensive unit has not been impressive this season, despite having a 3-1 overall record. They held Nebraska to 14 points in Week 2 but gave up 42 points to TCU in Week 1, 35 to Colorado State in Week 3 and 42 to Oregon last week. They are ranked #122 in the country in opposing yards per game, #105 in opposing passing yards per game and #118 in opposing rushing yards per game. USC’s offense is currently ranked #1 in the country in scoring, so we do not see this Colorado defense having an answer here.

We see value in USC -21.5 (-110 at BetMGM Sportsbook) in this game, and that is our #8 USC vs. Colorado pick. Click here to place a wager and to take advantage of BetMGM Sportsbook to score a $1,500 first-bet offer.

How to Bet on USC -21.5 at BetMGM and Claim Your $1,500 First-Bet Offer

We have provided a step-by-step guide on claiming the BetMGM promotion, which will get you a $1,500 first-bet offer. The guide is here:

  1. Create an account at BetMGM Sportsbook
  2. Deposit at least $10 into your account
  3. Place a wager up to $1,500 using our #8 USC vs. Colorado picks

It is important to reiterate that you WILL NOT need to use a promo code to unlock this offer at registration. You can wager a minimum of $10 or a maximum of $1,500 on your very first bet and receive all of your bet back as a bonus bet if your wager does not win. So, register for a BetMGM account and fade or follow our expert #8 USC vs. Colorado picks to receive a first-bet offer of up to $1,500.

#8 USC vs. Colorado Odds & Betting Lines via BetMGM Sportsbook for Saturday, September 30th, 2023

We have highlighted our expert #8 USC vs. Colorado picks earlier in this article. Here are the latest betting odds and lines for today via BetMGM Sportsbook.

  • Spread: USC -21.5 (-110) vs. Colorado +21.5 (-110)
  • Money Line: USC (-1400) vs. Colorado (+800)
  • Total: Over 72.5 (-110) / Under 72.5 (-110)

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