Opening NFL Week 1 Odds, Betting Lines & Spreads for This Week's Games
The impending slate of NFL Week 1 is about to wash over a nation of passionate football fans in glorious fashion. One way to heighten your investment is to bet on some of the games. If so, you’re in luck because we have all the main market lines regarding each matchup for you to preview before placing your bets.
All the opening NFL Week 1 betting odds are listed below, courtesy of BetMGM Sportsbook, along with details of a $1,500 first-bet bonus available to new users and our experts’ favorite player prop bets.
Become a new member at BetMGM today to qualify for a first-bet offer that provides up to $1,500 back in bonus bets should you lose an opening wager using any of BetMGM’s opening NFL Week 1 odds.
NFL Week 1 Opening Betting Odds, Lines & Spreads at BetMGM Sportsbook
BetMGM Sportsbook has their odds and lines released for every Week 1 matchup. To get a read on all of their lines, sort through our listing below:
- Detroit Lions +6.5 (-110) vs. Kansas City Chiefs -6.5 (-110), Thursday at 8:20 PM ET
- Money Line: Lions (+240) vs. Chiefs (-300)
- Point Total: Over 54.5 (-110) / Under 54.5 (-110)
- Carolina Panthers +3.5 (-110) vs. Atlanta Falcons -3.5 (-110), Sunday at 1 PM ET
- Money Line: Panthers (+150) vs. Falcons (-185)
- Point Total: Over 39.5 (-110) / Under 39.5 (-110)
- Houston Texans +10 (-110) vs. Baltimore Ravens -10 (-110), Sunday at 1 PM ET
- Money Line: Texans (+375) vs. Ravens (-500)
- Point Total: Over 43.5 (-110) / Under 43.5 (-110)
- Cincinnati Bengals -2.5 (-110) vs. Cleveland Browns +2.5 (-110), Sunday at 1 PM ET
- Money Line: Bengals (-135) vs. Browns (+115)
- Point Total: Over 47.5 (-110) / Under 47.5 (-110)
- Jacksonville Jaguars -4.5 (-110) vs. Indianapolis Colts +4.5 (-110), Sunday at 1 PM ET
- Money Line: Jaguars (-225) vs. Colts (+180)
- Point Total: Over 45 (-110) / Under 45 (-110)
- Tampa Bay Buccaneers +6 (-110) vs. Minnesota Vikings +6 (-110), Sunday at 1 PM ET
- Money Line: Buccaneers (+200) vs. Vikings (-250)
- Point Total: Over 45.5 (-110) / Under 45.5 (-110)
- Tennessee Titans +3 (+100) vs. New Orleans Saints -3 (-120), Sunday at 1 PM ET
- Money Line: Titans (+145) vs. Saints (-175)
- Point Total: Over 41 (-110) / Under 41 (-110)
- San Francisco 49ers -2.5 (-110) vs. Pittsburgh Steelers +2.5 (-110), Sunday at 1 PM ET
- Money Line: 49ers (-145) vs. Steelers (+120)
- Point Total: Over 41 (-110) / Under 41 (-110)
- Arizona Cardinals +7 (-110) vs. Washington Commanders -7 (-110), Sunday at 4:25 PM ET
- Money Line: Cardinals (+240) vs. Commanders (-300)
- Point Total: Over 38 (-110) / Under 38 (-110)
- Green Bay Packers +1 (-110) vs. Chicago Bears -1 (-110), Sunday at 4:25 PM ET
- Money Line: Packers (+100) vs. Bears (-120)
- Point Total: Over 43 (-110) / Under 43 (-110)
- Las Vegas Raiders +3.5 (-110) vs. Denver Broncos -3.5 (-110), Sunday at 4:25 PM ET
- Money Line: Raiders (+155) vs. Broncos (-190), Sunday at 4:25 PM ET
- Point Total: Over 44 (-110) / Under 44 (-110)
- Miami Dolphins +3 (-110) vs. Los Angeles Chargers -3 (-110), Sunday at 4:25 PM ET
- Money Line: Dolphins (+135) vs. Chargers (-160)
- Point Total: Over 51 (-110) / Under 51 (-110)
- Philadelphia Eagles -4 (-110) vs. New England Patriots +4 (-110), Sunday at 4:25 PM ET
- Money Line: Eagles (-190) vs. Patriots (+155)
- Point Total: Over 45 (-110) / Under 45 (-110)
- Los Angeles Rams +5.5 (-110) vs. Seattle Seahawks -5.5 (-110), Sunday at 4:25 PM ET
- Money Line: Rams (+200) vs. Seahawks (-250)
- Point Total: Over 46 (-110) / Under 46 (-110)
- Dallas Cowboys -3 (-115) vs. New York Giants +3 (-105), Sunday at 8:20 PM ET
- Money Line: Cowboys (-175) vs. Giants (+145)
- Point Total: Over 46.5 (-110) / Under 46.5 (-110)
- Buffalo Bills -2.5 (-110) vs. New York Jets +2.5 (-110), Monday at 8:20 PM ET
- Money Line: Bills (-140) vs. Jets (+115)
- Point Total: Over 46.5 (-110) / Under 46.5 (-110)
There you have it, all 16 main-market odds and lines for NFL Week 1 at BetMGM. If you’d like any of these, be sure to head to BetMGM with this link and place a bet. New users get to do so with up to $1,500 in bonus bets back should their first bet lose.
How to Take Advantage of BetMGM’s NFL Odds & Lines to Snag a $1,500 Bonus
If you want to pair any of the opening NFL Week 1 odds with the BetMGM first-bet bonus, first ensure you are 21, have never before registered with BetMGM and are in an eligible state. Once you check these boxes, follow our guide to qualify for up to $1,500 back in bonus bets should your first bet lose:
- Create an account here – no BetMGM promo code is needed
- Deposit $10+ and browse the opening NFL Week 1 odds
- Wager up to $1,500 on any of these markets or our expert player prop picks detailed below
- If you win, receive your winnings like usual
- If you lose, receive bonus bets back of equal amount to your wager
That’s all there is to this sign-up bonus, and you can qualify for it with a wager on any sport or market. With Week 1 commencing in a couple of days, why not bet up to $1,500 fully insured on the best sport to wager on? If you bet more than $50, you will receive five bonus bets back should you lose. If you play it safer and lose, one bonus bet will be credited to your account. Join BetMGM today to snag this exclusive $1,500 bonus.
Expert NFL Picks: Our Favorite Player Prop Bets for Week 1
Before we leave you, we have our experts’ best player props concerning opening Week 1 NFL odds. Some of these odds have yet to be released, so in these cases, we are targeting player props to bet as soon as a line debuts.
Now that he has been made the highest-paid QB in the NFL, we expect Herbert to come out with plenty of motivation to light up the sky against a Dolphins secondary that struggled last year and is missing Jalen Ramsey to start this season. This game should be one of the highest-scoring and most exciting NFL Week 1 contests, so expect a shootout.
We expect new offensive coordinator Kellen Moore to turn the Chargers’ surprising inefficiencies around rather quickly, and the debut of a new-look offense could fool the Dolphins. With an embarrassment of riches in terms of playmakers around Herbert, we like the over on his passing yards regardless of where it's set at BetMGM.
Ridley has missed over a year of regular season action since his off-field issues sidelined him during his time with the Atlanta Falcons, which means many people have forgotten how talented this receiver is. He was one of the best in the NFL prior to these incidents and has already assumed the #1 pass-catching role for an MVP candidate in Trevor Lawrence. While some may expect a slow start for Ridley in his return to football, we like him to come out of the gates strong, with a chance to record north of seven receptions in Week 1.
If you have followed reports out of Green Bay’s camp at all, you know buzz around the rapport between rookie tight end Luke Musgrave and first-year starting quarterback Jordan Love has been glowing. Musgrave has proven an athletic freak through camp and the preseason, and he could find a role as a red zone target immediately against a Chicago defense that has struggled mightily against tight ends over the past couple of seasons. We believe in the hype and buzz surrounding Musgrave and like his +375 value to score at any point against a Bears defense with much to prove.
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