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49ers vs. Vikings Prediction, Best Bets & Odds for Monday, 10/23

49ers vs. Vikings Prediction with DraftKings

The San Francisco 49ers had their 15-game regular season win streak snapped this past Sunday, but perhaps the most important outcome is what we’ll learn from the injury statuses of Christian McCaffrey and Deebo Samuel. Thankfully, they’ll have an extra day of rest with the 49ers playing on Monday Night Football against the Minnesota Vikings.

With that in mind, we’ve provided our best 49ers vs. Vikings prediction paired with the latest DraftKings Sportsbook sign-up offer that provides all new members with multiple guaranteed bonuses.

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49ERS VS. VIKINGS PREDICTION: San Francisco -6.5 (-105 at DraftKings Sportsbook)

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49ers vs. Vikings Prediction for Monday Night Football on 10/23

When it comes to making our 49ers vs. Vikings prediction, it’s worth noting that the point spread has been swapping between 6.5 and seven points throughout the week. With seven being such a key number, it certainly makes a difference what it is when you go to lock in your 49ers vs. Vikings best bets.

However, with how impressed we’ve been with San Francisco, we’d take it at either number. The biggest question entering the season was with QB Brock Purdy, but he far exceeded any expectations for the last pick in the NFL Draft. We’re also expected to see McCaffrey, Samuel and Trent Williams on the field.

Meanwhile, Minnesota will still be without WR Justin Jefferson, so we’re expecting San Francisco to bounce back. That’s why our 49ers vs. Vikings prediction is focused on the away team.

49ers vs. Vikings Free Picks & Best Bets

Not having Jefferson is a major blow to a Vikings team that needs to put up points in order to win games. Their defense continues to struggle, and although last week’s 19-13 win may not demonstrate that, it was a game against a Chicago Bears team that had an injured Justin Fields, who was knocked out of the game.

A fair comparison to playing the 49ers is playing the Eagles, which the Vikings have done this season. They allowed 34 points, and we wouldn’t be surprised to see San Francisco do the same. After all, they had scored 30 points in eight straight games before the streak was snapped last week.

McCaffrey also extended his touchdown streak to 15 games, and again, we expect him to be on the field. That means the 49ers will have two MVP candidates on the field in McCaffrey and Brock Purdy. This week should be a welcomed relief to both of them, as going from the Cleveland Browns league-best defense to the poor defense of Minnesota should allow them to pad their stats a bit.

Expect big games from both, and ultimately, lead their team to help our 49ers vs. Vikings prediction of San Francisco -6.5 (-120 at DraftKings Sportsbook) come to fruition.

How to Bet $5 on 49ers -6.5 and Get $200 Win or Lose at DraftKings

We mentioned a multi-gifted DraftKings promo to go along with our 49ers vs. Vikings prediction, and here’s how to claim it using any 49ers vs. Vikings best bets:

  1. Use this link to create a new DraftKings account
  2. Deposit at least $5
  3. Place a wager of at least $5

Those few quick and easy steps will secure you $200 in bonus bets plus a No Sweat Bet token valid for Same Game Parlays that include at least three legs. That qualifying bet can also be on anything, not just our 49ers vs. Vikings prediction. All without needing a DraftKings promo code, so just click right here to get started.

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49ers vs. Vikings Odds via DraftKings Sportsbook for MNF on October 23rd, 2023

In terms of our 49ers vs. Vikings prediction, and based on the 49ers vs. Vikings odds at DraftKings Sportsbook, a $12 bet profits $10 as long as San Francisco wins by at least seven points:

Point spread:

  • San Francisco 49ers -6.5 (-120) vs. Minnesota Vikings +6.5 (+100)

Money line:

  • San Francisco 49ers (-298) vs. Minnesota Vikings (+240)

Total (over/under):

  • Over 44 (-108) vs. Under 44 (-112)

49ers Injury Report Ahead of MNF, Will Deebo Samuel, Trent Williams & Christian McCaffrey Play?

With the 49ers entering the season as one of the top two contenders in the NFC alongside the Philadelphia Eagles, there was no doubt that they would have a few primetime games. Well, a Monday Night Football game couldn’t have come at a better time.

Not only were McCaffrey and Samuel both unable to finish last week’s game, but OT Trent Williams - arguably the best in the game - was also injured. Now, all three of them have an extra day of rest thanks to MNF, and the latest reports are that all three avoided long-term injuries. With that in mind, it only further supports our 49ers vs. Vikings prediction. So, if that also provides confidence in you locking in your best bets, be sure you join DraftKings today for your guaranteed rewards.

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