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Cardinals vs. 49ers Prediction, Picks, Best Bets & Odds for 10/1

Cardinals vs. 49ers Prediction with BetMGM

The Arizona Cardinals face another major uphill task on Sunday, heading to Santa Clara to take on the dominant San Francisco 49ers. We have a Cardinals vs. 49ers prediction that you are going to want to hear about, setting you up to win on Sunday.

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ARIZONA CARDINALS VS. SAN FRANCISCO 49ERS: BET ON CARDINALS +14 (-110) AT BETMGM SPORTSBOOK

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NFL Week 4 Prediction for Arizona Cardinals vs. San Francisco 49ers on Sunday, 10/1

The talk of the NFC has been the dominance of the 49ers so far this year. They have easily handled all competition, which is the biggest reason why they are 14-point favorites heading into their game against the Cardinals on Sunday afternoon.

Our Cardinals vs. 49ers prediction has the Cardinals covering that 14-point margin. We won’t go so far as to predict another major upset, but the Cardinals showed serious fight last week against the Dallas Cowboys and 14 points is a lot to win by in the NFL, even in a sizable mismatch.

The major bright spot against the Dallas Cowboys last week for the Cardinals, aside from winning, is the performance the ground game pulled off. James Conner had 98 yards and a touchdown on just 14 carries, good for 7.0 YPC. Rondale Moore chipped in 54 yards on 3 carries (18.0 YPC), and Joshua Dobbs even had 55 rushing yards (9.2 YPC).

If the Cardinals are going to shoot for the moon and earn a second major upset, the ground game is going to be integral. Controlling the clock, wearing down the defense, and keeping the 49ers offense off the field are all very important. At the very least, keeping the offense off the field will help limit the damage and allow the Cardinals to safely cover that monstrous 14-point spread.

Cardinals vs. 49ers NFL Best Bets & Picks Targeting the Over (44.5, -105)

Our Cardinals vs. 49ers prediction may be surprising but we love the over in this one. Our Cardinals vs. 49ers best bets focuses on the over (44.5, -105) and it may not be as high as it looks. It’s the perfect opportunity to tail our Cardinals vs. 49ers prediction and win big.

The 49ers have been excellent offensively so far, scoring 30 points on the nose in all three games. The Cardinals showed real fight against what was considered to be a superior opponent. They put up 28 points on a Dallas defense considered to be among the best out there. Given how often the 49ers score, even 16-20 points from the Cardinals will be enough to hit the over safely in this one.

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How to Bet Up to $1,500 on the Cardinals & Not Worry About the Outcome at BetMGM Sportsbook

Whether you decide to tail our Cardinals vs. 49ers prediction or go with your own Cardinals vs. 49ers picks, there is only one way to do it. Using BetMGM Sportsbook, you can ensure that your first bet is covered so that even when you lose, you win.

Sign up for a new account with BetMGM Sportsbook and don’t worry about a promo code as you do not need one. You will, however, need to make a deposit of at least $10 in order to qualify. When ready, place your first bet (our Cardinals vs. 49ers prediction is a good place to start) and hope for a winner. If you lose, you will get your first wager back in bonus bets totaling up to $1,500. 

If you lose $50 or more, you will be refunded with five bonus bets each worth 20% of your original stake. If you lose $49 or less, you’ll get a single bonus bet back worth the entirety of your lost stake.

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Betting Odds & Lines at BetMGM for Cardinals vs. 49ers NFL Week 4 on Sunday, October 1st, 2023

When making a Cardinals vs. 49ers prediction, the most important thing to consider is the Cardinals vs. 49ers odds. If you thought the 12.5-point line against the Cowboys was ugly, it gets a little worse as the Cards head to Santa Clara to take on the juggernaut 49ers.

Before we get to our Cardinals vs. 49ers best bets, let’s take a closer look at the odds. The 49ers are 14-point favorites and an incredibly -900 to win outright. The Cards are a whopping +600 money line odds, providing some serious value if you want to go against our Cardinals vs. 49ers prediction and go with the money line instead.

  • Money line: Arizona Cardinals (+600) vs. San Francisco 49ers (-900)
  • Point spread: Arizona Cardinals +14 (-110) vs. San Francisco 49ers -14 (-110)
  • Game total: Over 43 (-110) vs. Under 43 (-110)

Cowboys vs. Cardinals Score Last Week

A factor that went into our Cardinals vs. 49ers Picks was the outcome of last week’s game against the Cowboys. The Cardinals put their best foot forward and upset one of the best teams in the league. It doesn’t seem to have impacted the Cardinals vs. 49ers odds all that much, but that’s another story.

The Cardinals built a steady lead against the previously dominant Cowboys, taking a 21-10 lead into halftime. There was a late push by the Cowboys, but the Cardinals held strong, getting to Cowboys’ QB Dak Prescott enough to disrupt his rhythm and force a critical interception in the end zone with about four minutes left. It was a shocking upset, to say the least, leaving the Cowboys with more questions than answers, and providing some reasons for confidence for the Cardinals.

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