Chargers vs. Chiefs Prediction, Picks, Best Bets & Odds for Sunday, 10/22
If it feels like you haven’t seen Patrick Mahomes, Travis Kelce and the Kansas City Chiefs in a while, that’s because they were featured on Thursday Night Football in Week 6. That victory got them to 5-1 on the year, and this week they host the Los Angeles Chargers in hopes of extending their lead in the AFC West.
With a divisional rivalry on deck, our experts have provided their best Chargers vs. Chiefs prediction, and alongside it is a breakdown of a guaranteed $200+ FanDuel Sportsbook promo that you can claim using any Chargers vs. Chiefs picks.
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CHARGERS VS. CHIEFS PREDICTION: Kansas City -5.5 (-110 at FanDuel Sportsbook)
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Chargers vs. Chiefs Prediction for Sunday's AFC West Matchup, 10/22
As mentioned, the Chiefs are coming off not just a victory, but their fifth straight win after falling on the opening night of the 2023-24 season. That was a close 21-20 loss to the Detroit Lions, and now that we’ve seen the Lions move to 5-1 themselves, that loss doesn’t seem nearly as bad as analysts were speculating at the time.
In terms of the Chargers, they continue to be involved in close games that ultimately don’t go their way. That was the case on Monday Night Football just a couple of days ago in a 20-17 loss to the Dallas Cowboys. As for this matchup, we’d consider adding the under to your Chargers vs. Chiefs picks with what we’ve seen from these teams thus far.
However, that’s more of a lean, and our best Chargers vs. Chiefs prediction is focused on backing Kansas City in terms of the point spread, so let’s break down why.
Chargers vs. Chiefs Free Picks & Best Bets
Given that these are AFC West rivals, they are all too familiar with one another. They’ve also been compared even more than usual in recent seasons given that they feature two of the best young QBs in Mahomes and Justin Herbert.
With Mahomes having won two MVPs, two Super Bowls and two Super Bowl MVPs, it’s safe to say he’s proven to be the better option. That certainly helps support our Chargers vs. Chiefs prediction that backs KC to win by at least six points. In fact, it’s worth noting that getting this number under seven points while the Chiefs are at home is quite surprising.
Regardless, we’ll happily take the value. Admittedly, the Chargers have indeed played Kansas City tough in recent matchups. However, all games are not equal, and LA is yet again dealing with injuries. For once, it’s not WR Keenan Allen’s hamstring and instead it’s WR Mike Williams who is out for the season with a torn ACL.
He’s their big-play, deep threat, and even if he was on the field, we’re not sure Herbert could even take advantage. Herbert injured his hand two weeks ago and it clearly bothered him against the Cowboys. It bothered him so much that he wasn’t even comfortable taking snaps under center.
Having RB Austin Ekeler back healthy is certainly a benefit, but at the end of the day, it’s a tough task for a back of his small stature to get through a defensive line led by Chris Jones. That’s all without mentioning the rest advantage as well. Kansas City has been off since last Thursday night, while LA is on a short week having played on Monday night.
Taking everything above into consideration, our best Chargers vs. Chiefs prediction is on Kansas City -5.5 (-110 at FanDuel Sportsbook).
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Chargers vs. Chiefs Betting Odds & Lines Provided by FanDuel Sportsbook for Sunday, October 22nd, 2023
If you’d like to target our Chargers vs. Chiefs prediction with your qualifying bet, we have the latest odds at FanDuel Sportsbook for their matchup on Sunday below:
Point Spread:
- Los Angeles Chargers +5.5 (-110) vs. Kansas City Chiefs -5.5 (-110)
Money Line:
- Los Angeles Chargers (+190) vs. Kansas City Chiefs (-230)
Total (over/under):
- Over 48.5 (-105) vs. Under 48.5 (-115)
Based on those prices, an $11 bet on our Chargers vs. Chiefs prediction of Kansas City -5.5 profits $10 as long as they win by at least six points.
Chargers vs. Chiefs Injury Report, Will Justin Herbert Player Play?
We mentioned LA’s injury concerns when breaking down our Chargers vs. Chiefs prediction, and here are some notable names from both sides. It’s worth mentioning that until Thursday and Friday practices wrap up, we may not see Herbert listed at all.
LA Chargers:
- Raheem Layne: Questionable
- Deane Leonard: Questionable
- Alohi Gilman: Questionable
KC Chiefs:
- Justin Watson: Questionable
Be sure to take the above into account and also monitor throughout the weekend before locking in your Chargers vs. Chiefs picks. Also make sure to become a new member at FanDuel to place them to guarantee yourself $200 in bonus bets and three months of free NBA League Pass.
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